Exact(56)
Similarly, verapamil, but not tanshinone-1, significantly sensitized KB/VCR cells to vincristine but did not affect the sensitivity of KB/VCR cells to tanshinone-1.
A clinically achievable concentration of Ribavirin (10 μ M), which was not cytotoxic to primary CLL lymphocytes in culture, significantly sensitized 76% of the samples tested to FLU with the sensitization index (R) ranging from 1.25 to eightfold.
Interestingly, doxorubicin and docetaxel significantly sensitized both ALDH− and ALDH + cells; however, ALDH− cells were more sensitive to these agents than the ALDH + cells and commercial BCSCs.
Pretreatment of A375M cells with IκBα/scFvMEL significantly sensitized melanoma cells to ionizing radiation assessed using a clonogenic survival assay.
Pretreatment of A375 cells with GrB/scFvMEL significantly sensitized melanoma cells to ionizing radiation assessed using a clonogenic survival assay.
VKJP1 and VKJP3 significantly sensitized ABCG2-expressing cells to established substrates of ABCG2 including mitoxantrone, SN-38, and doxorubicin in a concentration-dependent manner, but not to the non-ABCG2 substrate cisplatin.
Structure activity relationship analysis showed that aromatic substituted aliphatic amine at the 24-positions (groups V) effectively and significantly sensitized P-gp overexpressing multidrug resistant (MDR) cells to anticancer drugs, such as docetaxel (DOC), vincristine (VCR), and adriamycin (ADM).
Similar(4)
However, mutants failed to significantly sensitize cells to FasL (Fig. 3C).
As has been reported with other DAC inhibitors, AR-42 significantly sensitizes CLL patient cells to TRAIL.
Over-expression of catalytically inactive caspase-8 and -10 in I9-2e cellslightlyly increased annexin-V labelling but failed to significantly sensitize cells to FasL (see Fig. 3).
Our results indicated that imatinib (1, 2.5 and 5 µM) did not significantly sensitize the response of control parental HEK293-pcDNA3.1 cells, or reverse resistance in HEK-MRP7-2 transfecellscells, (Table 1) to doxorubicin.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com