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The baseline fingerprints, ECFC0 and MACCS, were indeed found to be statistically significantly ranked last of all fingerprints in this study using "early recognition" evaluation methods.
Simulations associated with space closure orthodontic treatment were ranked as the most attractive smile and significantly ranked higher by dental professionals than patients and laypeople.
In accordance with the structure-activity findings mentioned before, BI1 stands apart from the four other indolinones with 5 significantly ranked pathways and the smallest overlap with the other indolinones.
However, pathways such as the Aryl Hydrocarbon Receptor Signaling and the LPS/IL-1 mediated inhibition of RXR function are also significantly ranked high for up to six compounds indicating a more general effect like a xenobiotic response to NCE treatment rather than a true compound specific effect.
When participants were asked to rank their top three choices for organisms in need of a POCT for STIs, Chlamydia trachomatis was significantly ranked as the top priority for development of new POCT by 62% of participants (p<0.05), followed by detection of early seroconversion of HIV infection (14%), and a POCT for syphilis (8%).
Systemic Complaints questionnaire responses were significantly ranked as fibromyalgia > back pain > normal.
Similar(51)
The action-based and the top-down consolidation measures also exhibit a roughly similar average (respectively, 1.2 per cent of GDP and 0.8percentnt of GDP, respectively) and a fairly high (0.38), statistically significantly rank correlation.
Furthermore, while helix/strand density does not significantly correlate (i.e., linearly) with the evolvability index (P = 0.375 for Pearson's correlation test, one-tailed), it does significantly rank correlate with the evolvability index (P = 0.0169 for Spearman's rank correlation test, one-tailed).
Factors remaining independently and significantly associated ranked: (a) longer treatment with lithium, (b) lower mean daily dose of lithium carbonate, (c) higher mean serum lithium concentration, (d) older age at the time of assays, (e) co-occurring medical illness (Table 8).
Indeed, the GCNF PWM that is significantly well ranked among genes from cluster 12 is closely related to several PWMs for Drosophila NRs (Additional file 1: Figure S4).
Experimental results on the datasets of TREC web track, OHSUMED, and a commercial web search engine show that with the use of the proposed query-level loss function we can significantly improve ranking accuracies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com