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In a book published in 1977, I said, "Alaska is a foreign country significantly populated with Americans".
Tumors can be significantly populated with macrophages, with the degree of macrophage infiltration being associated with disease outcome (reviewed in [ 48]).
In summary, the prevailing intracellular concentration of GSH requires a target dithiol motif to bind with a Kd of less that about 10 nM to be significantly populated with the As III) species.
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For the compounds with a significantly populated IMHB conformation (syn- A, E, and H), a population increase is calculated upon temperature decrease.
Most protein domains fold in an apparently co-operative and two-state manner with only the native and denatured states significantly populated at any experimental condition.
The folding-unfolding of hPCNA in the presence of urea or GuHCl shows a biphasic behavior consistent with a partially unfolded intermediate state which is significantly populated in the transition zone (Fig. 2C and 2D).
Analysis of NOESY data obtained at multiple mixing times did not reveal chemical exchange cross-peaks for either the Tg CH3 and Tg H6 protons, consistent with the conclusion that only one epimer was significantly populated in the sample (10).
Reverse phase HPLC clearly showed the presence of at least two isomeric forms of the peptide that were significantly populated.
Genetic clustering of these specific gene sets with KEGG (Kyoto Encycolpedia of Genes and Genomes) signaling pathway annotation also revealed more significantly populated pathways for the males (6) compared to the females (4).
Only when this intermediate of aggregation is significantly populated does the process of aggregation proceed to formation of large aggregates.
In such (un folding pathways, only the native and denatured states are significantly populated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com