In these conditions, Ca2+ influx appeared to be significantly greater following depletion of phosphoinositides, which may suggest an additional negative role for phosphoinositides in SOCE.
We noticed that upon arsenite treatment, significantly less number of Dvl2 transfected cells displayed SGs, suggesting a negative role for Dvl in SG assembly (Fig. 1D,E).
Consistent with its negative role in Wnt signaling, Axin ubiquitination with K29-linked polyubiquitin chain is significantly suppressed by Wnt3a stimulation.
Most caregivers take up their role without prior knowledge or experience, and the associated stress may have a significantly negative impact on the caregivers' QoL [17].
In this study our focus was on finding parameters that can significantly improve the function, although some of the parameters may exhibit a large negative z-score indicative of a negative role in the function.
Significantly, our results on patient samples further indicate that these channels are expressed at high levels during active disease, indicating a negative role played by these VGCC during M. tuberculosis infection.
Notably, several OsGH9 family members have recently been identified with a role in cellulose crystallinity modification [ 43], and the Ara substitution degree of xylans in Miscanthus displays a significantly negative correlation with the cellulose crystalline index [ 58].
They were playing a very negative role".
Mindfulness could make things worse and have a significantly negative effect on the person.
So far, GDP releases have not turned into significantly negative territory.
