Sentence examples for significantly more constrained from inspiring English sources
Indeed, it appears that the strength of the evolutionary constraints operating at the nucleotide level are not equal between the isoforms, with H2A.Z-2 being significantly more constrained than H2A.Z-1 [ 24].
In comparing between types of tasks, we notice that the more challenging open-ended tasks benefit significantly more than constrained item types by the use of DNN-HMMs.
We show that the new approach can identify significantly more degenerate constrained sequences than rate-based methods.
Our analyses demonstrate that H2A.Z-2 is not only subject to a strong purifying selection but it is significantly more evolutionarily constrained than H2A.Z-1.
When the geometry within the units making up the framework is significantly more strongly constrained than the geometry of the links between them, the properties of the structure can be strongly influenced by low-frequency collective modes of motion.
Our analyses demonstrate not only that H2A.Z-2 isubjectctoto a strong purifying selection (as most histones are) but that in fact it is significantly more evolutionarily constrained than H2A.Z-1.
(Posterior samples obtained from multi-modal posteriors can be clustered and analysed separately using the heuristics in MultiNest [ 10].) Scaling the standard deviation by the mean shows a 10-fold difference between k I and k d, indicating that the transcription threshold k I is significantly more tightly constrained (by the model and the data combined) than the protein degradation threshold k d.
Expression breadth is also significantly correlated with d N/d S, with broadly expressed genes being more constrained on average (fig. 3).
In addition, we find that genes that are part of many pathways (ten or more) are even more constrained than genes occurring in a single or a few pathways, as they show significantly lower DN/DS and PN/PS ratios (P < 1e-6, Mann–Whitest tesupplementarytary fig. S3, Supplementary Material online).
Mr Osborne is far more constrained.
Clinton may have been even more constrained in her responses.
