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Xing and Lee [28], [29] noted that RNA sequences from alternatively spliced exon/intron boundaries leads to selection pressure for nucleotide sequence conservation in these regions while there is significantly less conservation in constitutive exons.
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Indeed, when the sequence conservation levels of target sites identified by the two methods were compared, Made1 related targets were found to be significantly less conserved, on average, than miRanda predicted targets (conservation scores: Made1 targets = 0.082±0.017 miRanda targets = 0.319±0.007; t = 11.27 P = 5.7e-29 Student's ttest).
Indeed, we found that the mean per-gene phyloP score calculated based on a 46-way primate comparison was significantly reduced (reflecting less conservation) for genes with detectable eQTL in both species, and greatest for genes in which eQTL were not detected in either case (p < 10−53; Figure 3A).
Results indicated that residents with very positive environmental and water conservation attitudes consumed significantly less water in total and across the behaviourally influenced end uses of shower, clothes washer, irrigation and tap, than those with moderately positive attitudinal concern.
The blood conservation device group lost significantly less blood for diagnostic testing (63 ml vs. 133 ml for controls), but the study failed to demonstrate a significant fall in Hb levels between admission and discharge when comparing the two groups [24].
Conservatives are significantly less likely to trust science than liberals.
In summary, in all trials the volume of blood taken for diagnostic testing between the blood conservation devices and control groups was significantly less; however, only in the larger trials did this result in a reduced rate of fall in Hb.
Because the patients who were exposed to radiotherapy had all chosen breast conservation therapy, their clinical stage was significantly less advanced, and the proportion of patients who underwent axillary lymphadectomy was significantly smaller than that in the no-radiotherapy group.
The results also show that the Landscapes designated after 2000 as high priority conservation zones by the Congo Basin Forest Partnership had undergone significantly less deforestation and forest degradation between 1990 and 2000 than the rest of the Central African forest.
The "stewardship & 30% MR" scenario rebuilds the stock biomass to the highest level, but provides significantly less catch to the fishery, indicating that this is a more conservation-minded strategy which trades off against economic gain.
In case of within-species conservation of the trait, we expect that species' artificial nodes account for significantly less variability than random expectations (significant left-tailed P-value for Sc).
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