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The inclusion of a placebo control would have provided greater clinical meaning, however it would have required a significantly larger study population.
The inclusion of a comparative treatment agent may have provided additional information, but would have required a significantly larger study population.
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Significantly larger studies of African-American women would be needed to address that question more completely.
Moderator analyses showed that the effect was significantly larger in studies that measured self-care as a continuous versus categorical variable (P = 0.001).
Because of the precious value of tissues represented in TMAs from large cohorts, we have tested 33 proteins by immunohistochemistry using this cohort of 160 patients in order to identify promising biomarkers for use in significantly larger validation studies [ 62].
The size of the protocol studied in this paper is significantly larger than case studies, including various abstract versions of the same protocol without bus-collision handling, reported previously in the community of real-time verification.
We previously found that the effect of statins on atherosclerosis efficacy outcomes was significantly larger for animal studies sponsored by non-industry sources versus studies sponsored by industry [ 21], but a meta-analyses of the effects of thiazolidiones on glucose reduction in animals had conflicting results [ 23].
The aim of this study, which was significantly larger than the previous studies highlighted, was to assess the association between circulating angiogenic (PlGF) and antiangiogenic (sFlt-1 and sEng) factors and the risk of preeclampsia in women with type 1 diabetes.
The team used genetic information from more than 1,200 people, significantly larger than previous studies in this area.
Traditional cookstoves had an average PM emission factor of 8.2 g kg−1 – significantly larger than previous studies.
However, our analysis included a significantly larger numbers of studies, was not limited to dyspnoea, as people may present acutely with several different symptoms, and evaluated the accuracy at specific cut-off points to inform current clinical practice.
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