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Our cellular imaging results showed that silica-coated CdSe QDs were significantly internalized into cytoplasmic vesicles and produce the good fluorescence in and around the cells (both stem and cancer cells) (Figure 6).
Figures 5 and 6 document by independent methods that sarcolemma in intact hearts is significantly internalized upon reoxygenation after an anoxic episode.
As CD21 is well-known to exist in a complex with CD19 (Fearon & Carroll, 2000) and CD21 is not significantly internalized (Fig 1), we hypothesized that CD21 bound to CD19 and prevented anti-CD19 antibodies from internalizing.
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The finding that eosinophils in asthmatic lungs significantly internalize AuNP is important for the application of nanocarriers as drug delivery systems for inhalation therapy.
However, even the moderately expressing Namalwa and Daudi cells (Fig 1C,D) and the higher expressing ARH77 and Raji cells (Fig 1E,F) failed to significantly internalize this antibody.
Both cell lines lacked the capacity to significantly internalize TF‐LPA above baseline levels (Fig 1H), strongly arguing against an important role for phosphorylation explaining the loss of function of PRG‐1R346T in TF‐LPA internalization, however, pointing to the need of S347 at this position.
Interestingly, heat-inactivated (Fig. 3B) or lightly fixed (Fig. 3C) parasites were significantly less internalized by the non-professional phagocyte cell lines, indicating that the efficient uptake process characteristic of T. cruzi EAs was induced by the live parasites.
Recent meta-analyses suggest that cognitive-behavioural interventions targeted at emotional resilience for adolescents can significantly reduce internalizing symptoms and decrease the risk for future internalizing symptoms compared to control groups [ 17– 17].
Interestingly, OVA coupled to oleoyl liposomes but not stearoyl liposomes were internalized significantly by APCs even in a 4°C environment.
These divergent phenotypes result from the differential processing of the abnormal immunoglobulins through the receptors on mesangial cells which lead to internalization and delivery of the light chains of AL-amyloid to the lysosomes, where production of amyloid occurs while the abnormal immunoglobulins associated with MIDD are not internalized significantly [ 17, 19, 20].
The GNPs of larger size or conjugated with OVA were internalized with significantly larger amount.
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CEO of Professional Science Editing for Scientists @ prosciediting.com