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"significantly impede" is correct and usable in written English.
It means to hinder or obstruct something in a significant or notable way. Example: The heavy rain significantly impeded the progress of our outdoor project, forcing us to delay it until the weather improved.
Exact(53)
Nevertheless, for all their bulk, these constructions do not significantly impede movement.
Federal Reserve officials have said that the current standards significantly impede the availability of loans.
Western sanctions that take effect this summer will significantly impede the export of Iranian crude.
"And although the potential end of passporting rights does significantly impede the UK financial sector, it has far less impact on fintech than for banks".
Experts and lawyers who have studied arbitration cases say that process, if enacted, could significantly impede Ms. Carlson's chances of prevailing.
The European Commission concluded the deal "would not significantly impede effective competition" in Europe, it said in a statement.
Similar(6)
The political valence in these cases significantly impedes the practice of good psychiatry".
"It is clear that the F.A.A.'s delay has significantly impeded the progress of our investigation," the statement said.
The panel said that the city's refusal to turn over the information had "significantly impeded" its investigation.
This, of course, significantly impedes capital formation, future economic growth, and further employment expansion.
In a statement, the commission said that "the city's failure to produce these important documents has significantly impeded the commission's investigation".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com