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Although this modification provides a significantly higher coverage of probe ssDNAs and longer-term stability [7, 8], non-specific bindings and aggregations among the DNA molecules significantly decrease its sensitivity.
The generalized rules that underlie our model have significantly higher coverage.
Interestingly, in postnatal development no RTE group displays a significantly higher coverage for proximal loci than for genic loci, and furthermore, for all RTE groups, genic loci have significantly higher coverage than loci distal to genes.
The analysis by occupational category showed significantly higher coverage for paramedical staff (26%) than for physicians and pharmacists (19%) (p<0.01).
There was significantly higher coverage in the general population for two seasons: 2003/04 (p = 0.032) and 2005/06 (p = 0.018).
For persons in the combined target group, a significantly higher coverage rate was observed compared to the non-target group respondents (Fig. 2d).
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For all types of RTEs, the average piRNA coverage of younger elements is significantly higher than coverage of older elements (Additional File 1, Table S2).
Both methods yielded significantly higher average coverage per gene than whole-exome sequencing and had substantially fewer exons with less than tenfold coverage.
Addition of ComDT to the HF approach resulted in significantly higher treatment coverage in the HF + ComDT area compared with the HF area during CHW1, CHW2, CHW3 and CHW4, with ORs (and 95% CIs) of a child being treated in the HF + ComDT area of 2.17 (1.90–2.48), 3.07 (2.68–3.52), 11.17 (9.25–13.48) and 5.07 (4.27–6.01), respectively.
Among non-priority adults, chiropractic users had significantly higher vaccination coverage levels for all vaccines compared to never CAM users.
Past CAM users had significantly higher vaccination coverage levels for influenza and pneumococcal vaccines when compared to recent CAM users.
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