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Significantly higher binding was noted at 22 and 37 °C as compared to that at 0 °C.
Compared with the pristine CNTs, the functionalized CNTs system has significantly higher binding energy value and shorter distance between the glycine and the nanotube surface.
In conclusion, the modified EGF had significantly higher binding affinity for apatite and titanium than soluble EGF, and the bound EGF significantly enhanced cell growth by long-lasting activation of intracellular signal transduction.
The results indicated that P1A6E and P3F2 had a significantly higher binding affinity than SS1 and C10 to MSLN-expressing cells (MFI value in PANC-1-MSLN cells: scFv-P1A6E: 327.5, scFv-P3F2: 308.8, scFv-SS1: 48.9 and scFv-C10: 46.8; MFI value in CHO-K1-MSLN cells: scFv-P1A6E: 452.3, scFv-P3F2: 445.1, scFv-SS1: 65.5 and scFv-C10: 80.2).
In contrast, patients with Alzheimer's disease with one or more T in C1236T, G2677T and C3435T had significantly higher binding potential values than patients without a T. In addition, there was a relationship between binding potential and T dose in C1236T and G2677T.
The no-Ter/wild-type Ter signal ratio (−TER/+TER) is 0 for Cy5 and 0.12 for Cy3, consistent with significantly higher binding of the fusion protein to plasmid containing wild-type Ter as compared to plasmid without any Ter.
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A significantly high binding affinity was observed for the PKR-inhibitor to the MARK4 variants.
In our database of 46 TFs we found 6 pairs of TFs with significantly high binding sequence similarity (Fig 5).
However, van Nimwegen et al. [10] (supporting text) use a simple maximum-entropy argument to show that the additivity assumption on energy does imply the PWM model for binding sites, if one also makes the reasonable assumption that binding sites have a significantly higher expected binding energy than random sites.
[C]CB184 showed nonspecific binding to healthy tissue comparable to that observed for [C]PK11195, but it displayed significantly higher specific binding in those brain regions affected by the HSE.
However, contrast-enhancing lesions did show a significantly higher [11C]PBR28 binding compared to contralateral NAWM [3].
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