But for some this cost is significantly higher and can run into the thousands.
It also means that the risk of it returning is significantly higher, and my prognosis poorer.
Above all, you have to get consumers to accept significantly higher, and steadily rising, prices.
Studies have shown that success rates are significantly higher, and complications lower, at hospitals that do many of these operations.
Still, for those who want to buy now, yields are significantly higher and prices lower than they were in June.
Memory for the emotional scenes was significantly higher, and the vividness of the recollection was significantly greater.
But the Arab birthrate is significantly higher, and under the current trends, Arabs will outnumber Jews within the next 10 to 20 years, according to demographers.
In black townships rates of child mortality are significantly higher and life spans far shorter than in white neighbourhoods.
But now, with the campaign's cost significantly higher and less time to raise money and attract supporters between primaries, it is hard to imagine a candidate's emerging from the shadows on persistence alone.
While profits of £328m and a 28% rise in sales were in-line with forecasts, the company's net debt figure of £2.6bn was significantly higher and started traders speculating about a possible cash call.
Some Wall Street analysts believe the figures could be significantly higher, and the company might have to be bailed out or put into receivership and sold with the help of the government.
