The affinity constants determined on both, the purified receptor and LNCaP cells, indicated significantly higher affinity of the dimer.
Complementary target DNA hybridization was shown to have a significantly higher affinity constant (KA) than MM1 and MM2.
These results demonstrated that BtA bound to the receptor in BBMV with significantly higher affinity compared with Bt toxin.
Overall, the majority of target compounds displayed significantly higher affinity for σ1 receptors than for σ2 receptors (Tables 1, 2, 3).
Both H-pins bound with significantly higher affinity (ca. 100-fold) than their corresponding unlinked PyImPyIm 4 and f-ImPyIm 2 counterparts.
Reported Michaelis constants (KM) showed that IPS/MnTSPP had significantly higher affinity for cationic dyes than anionic dyes (lower KM for PNS and MB, higher KM for ARS and XO).
The chromatic experiments, complemented by transmission electron microscopy analysis and fluorescence quenching assays, also revealed significantly higher affinity early spherical aggregates of k-casein to anionic phosphatidylglycerol-lipids, as compared to zwitterionic phospholipids.
While these affinity clamps all had significantly higher affinity toward a target peptide than the underlying PDZ domain, two distinct types of affinity clamps were found in terms of target specificity.
Antibodies lacking the fucose residue, or having very low fucosylation content, have been demonstrated to have significantly higher affinity binding to FcγRIIIa, resulting in stronger NK cell-mediated, antibody-dependent cellular cytotoxicity (ADCC).
The detection principle based on hybridization combinations can occur between QDs-sDNA and complementary target DNA; moreover, QDs-sDNA can bind to GO with significantly higher affinity than QDs-dsDNA.
