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As for the diabetes-specific factors, microvascular complications and disease duration were the most significant predictors of HRQOL, each affecting negatively and significantly five SF-36 subscales.
Among all samples, we identified only six individuals with more than one mutation; significantly, five of them had two independent spliceosome gene mutations of different VAFs.
Six of seven studies on fish and amphibians document strong trends or significantly (five studies) altered sex hormone concentrations associated with atrazine exposure (Table 6).
Significantly, five patients in the phase I study had baseline CTC counts ⩾5 and three of these patients had their CTC counts reduced to <5 after 12 weeks of treatment.
In seven of these eight instances the PERR adjusted hazard ratios differed significantly from the Cox adjusted hazard ratios, and either did not differ significantly (five outcomes) or were more similar (two outcomes) to the trial hazard ratio.
Significantly, five chromosomes with neocentromeres have been described in which the alphoid array within which the centromere is normally formed is still present, three on chromosome Y, one on chromosome 3, and one on chromosome 4 [ 30].
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Most significantly, "two bathrooms makes for a happy marriage," Mr. Tartaglia said.
It is made up of clerics, theologians, psychiatrists, therapists and – most significantly – two survivors of priestly sex abuse.
Significantly four out of the past five Monte Carlo champions went on to reach the final at Roland Garros, two of them winning it.
Perhaps significantly, three of Cotterill's six victories have been 1-0 wins – a scoreline County had only produced once before this season.
Although the committee had spent nearly six months working on the constitution, some articles were changed significantly two days before the final vote, after the opposition had quit.
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