During uniform wall construction, synthesis of the pectin rhamnogalacturon backbone (RG1) was likely catalyzed by expression of galactofuronosyl-transferase 13-like (GAUT13 - Additional file 13) that significantly is essential for polarized pollen tube tip growth [ 65].
Knockdown of UHRF1 expression in cancer cells suppressed cell growth significantly, indicating that UHRF1 is essential for progression of cancers (Unoki et al, 2004).
We demonstrate that genes which have high connectivity (i.e. 'hub' genes) within a weighted co-expression network are significantly more likely to be essential for yeast viability.
However, when both ING1b and p53 proteins are present, apoptosis following DNA damage can be significantly enhanced, suggesting that they are essential for an appropriate cell stress response.
Most significantly, the unique transcription factor circuit essential for mouse ESC identity, self-renewal and pluripotency, is functionally operative in sustaining the reset human pluripotent state.
Although neither of the single mutants bound ATP, the D78N/H165Q double mutant bound ATP weakly but significantly, suggesting that additional residues are essential for ATP binding.
Responses to the question "Do you consider taking vitamins or other supplements such as minerals and herbs to be essential for health?" were significantly different between participants according to geographic location (adjusted OR for believing DS to be essential: 0.45 (0.72, 0.72) for West compared to East Coast participants; p = 0.001).
Cellular trafficking of neurotransmitters to presynaptic terminals is essential for neurotransmission, and significantly the genome of A. digitifera encodes a wide range of solute carrier neurotransmitter transporters, including a high affinity choline transporter and an acetylcholine-specific protein belonging to the major facilitator superfamily (MFS) of secondary transporters.
Transcript stability was significantly higher for essential genes [ 23] than for non-essential genes, for all growth rates considered (P-value < 0.05).
Significantly, the ZnF1 of TRAF6 is also essential for E2 interactions, but the mechanism for this is drastically different from that of RNF125.
