Sentence examples for significantly dose-dependent from inspiring English sources
A significantly dose-dependent increase of apoptosis in gonocytes appeared 6 h after irradiations with a dose of 0.5 Gy or more.
In the present study, we found that treatment of neurons with different concentrations of L-DOPA also resulted in a significantly dose-dependent increase in iron content, ferrous iron uptake and the expression of DMT1−IRE protein in cortical neurons.
Among the 501 parameters, 0, 54, 111, and 217 parameters showed significantly dose-dependent effects based on the Jonckheere-Terpstra test at FDR = 0.01, 0.05, 0.10, and 0.20, respectively [11], [17].
These are significantly dose dependent.
After 72 h of incubation the metabolic activity was significantly dose dependent reduced in all cell lines starting at a concentration of 0.5 μM PDA-66.
The inhibitory effects of both tamoxifen and metformin on the two cell lines were significantly dose dependent and at the concentration of about 8 μM tamoxifen or 20 mM metformin the cell survival curves began to drop.
Thus, combination therapy with a calcium antagonist and an ACE inhibitor provides blood pressure control equal to that of high-dose calcium antagonist monotherapy but with significantly fewer dose-dependent adverse experiences such as vasodilatory edema.
Microvessel density measurements were performed using computer image analysis of CD31-stained sections.Compared with controls, mice treated with ZD6474 showed a significantly reduced dose-dependent decline in breaking strength, both at POD 7 (P < 0.001) and at POD 28 (P < 0.005).
The expression levels of pro-collagen I α1 was not significantly decreased, but, the expression of procollagen III α1 was decreased significantly in a dose-dependent manner.
Nano copper up-regulated the CTR1 and SOD1 genes and down-regulated the relative expression of COX17, MT and ATOX1 genes significantly in a dose-dependent manner.
Uterine blood flow was also increased significantly in a dose-dependent manner by 98 ± 15, 216 ± 59, and 303 ± 56 mL/min, for the 1.25, 2.5, and 5 mg doses, respectively.
