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The phrase "significantly distinctive" is correct and usable in written English.
You can use it when you wish to emphasize that something is different in a meaningful or important way. For example, "The forest in the new conservation area is significantly distinctive from other nearby forests."
Exact(3)
The main reason is that the scene has the highly texture background and the static features of the small foreground objects are not significantly distinctive.
Two classes of HeLa cells with significantly distinctive migration patterns were observed during experiments: migratory and stationary.
Breakpoints were restricted to the boundaries between two adjacent DNA fragments with significantly distinctive log2 ratio values, reflecting different copy numbers.
Similar(57)
However, for the more realistic case of a finite bath, the different PSD's gave significantly more distinctive results, especially for fractional mass uptake values greater than about 0.7.
Drug nanocrystals comprise unique drug delivery platforms playing a significantly important and distinctive role in drug delivery and as such, the industry and academia are spending a lot of their time and money in developing the nanocrystal products.
A closing crack causes the dynamic behaviour of a vibrating system to be significantly nonlinear.The main distinctive features of such a vibrating system are the appearance of sub- and superharmonic resonances, and the significant nonlinearity of the vibration responses at sub- and superharmonic resonances (displacement, acceleration, strain, etc.).
We see that the corresponding dispersion relation becomes significantly different – a distinctive feature being the flat low-frequency band located at ∼ 0.15 above which the PnBG now appears.
That same year a Rolling Stone cover story hyping his talent and his distinctive albinism significantly raised his profile.
Significantly, the nations have distinctive areas of research strength.
The generalisability of the study's findings is relatively low, in common with most case studies, and is negatively impacted by relatively small numbers of participants and by the possibility that other nursing homes with different organizational frameworks may exhibit distinctive, potentially significantly different, results.
Because these poems are so significantly out-numbered by less distinctive pieces, it is frankly not surprising that his stock should be at so low.
More suggestions(15)
significantly significant
considerably distinctive
dramatically distinctive
much distinctive
significantly diverse
significantly different
significantly notable
significantly typical
significantly unique
strikingly distinctive
further distinctive
significantly specific
significantly distinguished
significantly separate
significantly differentiated
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com