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That erratic performance probably ended with Humana's significantly disappointing 1999 results.
The degree of mandatory probing in hospitals was less encouraging and all other types of health organisations claimed a significantly disappointing degree of proactive behaviour.
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Earlier this month RWE told investors in Germany that full-year figures for its UK arm would be "significantly below" the already disappointing levels achieved in 2014.
Take the BlackBerry Z10 smartphone, which, after disappointing sales, dropped significantly in price just a few months after release.
Rival BJ's Wholesale Club posted disappointing fourth quarter earnings, down significantly from a year ago.
The literature supporting such approaches is significantly more robust than the largely disappointing evidence on the use of genetic information to motivate behavior change (Hettema & Hendricks Dec 2010; Pollak et al. 2010; Resnicow et al. 2006).
The fact we're 0.2% down on services is very disappointing" "A bit disappointing, obviously significantly weaker than expected.
Thor needs to significantly up his game after the mildly disappointing, overly tinkered-with The Dark World, and that title hints at a pretty epic third instalment.
So far, the majority of medical treatments (apart BSC) assessed in advanced HCC have shown disappointing results and do not significantly change the natural course of the disease.
Turkish restaurants in New York, often disappointing in the past, have improved significantly with the growing popularity of Mediterranean food.
At a time when we urgently need to see more innovation and investment so Britain can better compete, it is disappointing that R&D spending fell so significantly during 2012," he said.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com