Sentence examples for significantly destabilizing from inspiring English sources

As described previously by Vinson and by Doig, phosphorylation of serine here was significantly destabilizing with respect to α-helicity, with the destabilizing effect of phosphorylation being larger than the stabilizing effect observed at the N-terminus.

Additionally, the heat and moisture was significantly destabilizing the atmosphere.

The replacement of Met at position 4 is expected to improve stability of AL324, indicating a significantly destabilizing mutation at one or more other positions.

None of the groups tested significantly destabilized the duplex.

The occupation of two CO molecules in each 51262 cage can therefore significantly destabilize the sI CO clathrate structure.

Thermostability studies also revealed that peptide insertion significantly destabilized the Trx scaffold by ∼ 27 °C.

Saddling current policyholders with soaring premiums will lead to an exodus from the program that will significantly destabilize it.

Especially when soluble carbonates are present, reductions in the pore solution pH, which often accompany ingress of sulfates, significantly destabilizes calcium monosulfoaluminate and accelerates AFt growth.

Replacing one ferrocene amino acid unit by the organic α-amino acid glycine at the C-terminal end (Fca → Gly) significantly destabilizes the secondary zigzag structure facilitating denaturation by DMSO.

From UV melting studies we showed a position dependent effect of UNA modifications such that quadruplexes with UNA modified loops are further stabilized whereas UNA modifications in stem of the G-quadruplex significantly destabilize the structure.

Instead, the base pairing of 2-amino-Adap with dG was significantly destabilized compared with that of Adap with dG, resulting in improved selectivity for 8-oxo-dG in the human telomere DNA sequence.