20 Overall, the purely enzymatic protocol excels by its significantly broader applicability compared to the chemoenzymatic procedure 10c, d for the following reasons: 1) it eliminates the harsh reaction conditions required for acid-catalyzed hydrolysis, which are incompatible with sensitive functional groups and 2) it is also applicable to retaining sulfatases (such as PAS).
Moreover, in a study of 258 individuals with unexplained HBM, HBM cases had significantly broader skeletal frames compared with controls (Gregson et al., 2012).
Overall, we noted that for the subset of enzymes that were characterized by HPLC, thermophilic enzymes had significantly broader substrate specificity compared to their mesophilic counterparts (pANOVA = 2 × 10 5).
The significantly broader tuning in AII compared to the other fields found here (Figs 3G and 6) was also reported for other mammals, i.e. the cat (Irvine & Huebner, 1979; Schreiner & Cynader, 1984), ferret (Bizley et al., 2005), rabbit (McMullen & Glaser, 1982), gerbil (Thomas et al., 1993), and owl monkey (Imig et al., 1977).
The increased standard deviations on the emotional signal blocks in the melancholic group is indicative of greater variability of mean bias values across participants, thus reflecting a significantly broader distribution of bias values compared to those values observed in the other groups.
It should be noted that the FWHM (full width half maxima) of Rh peaks was significantly broader (2.0 2.7 in our measurement) when compared to those of Rh standard (about 0.7 for pure bulk Rh2O3).
The resulting characterization is significantly broader and deeper than previous BitTorrent investigations: it compares multiple BitTorrent communities and investigates aspects that have not been characterized before, such as aggregate user behavior and resource contention.
Their high carrying capacity of 20,000 150,000 drug molecules/liposome, allows for the use of a significantly broader range of moderate-to-high potency small molecule drugs when compared to the comparably few subnanomolar potency maytansinoid- and auristatin-based immunoconjugates.
Overall, use of four peptide sets detected significantly broader responses; six more participants showed Gag T-cell recognition when stimulated with four sets of Gag peptides compared to when only clade B peptides were evaluated, (13 of 21 responders compared to 7 of 21 respectively), table 2 and figure 3b.
Our Premier League relationship is significantly broader than our MLS relationship".
