Sentence examples for significant ups and downs from inspiring English sources

He also accepted the significant ups and downs that the country would experience along the way.

However, for low FVII injuries, the size of the clot is not stable, with some significant ups and downs in the size.

In past decades, international crude oil prices experienced significant ups and downs and attracted extensive attention across the academic and industrial communities (Wu and Zhang 2014).

The Scorecard feature captures significant ups and downs from a Web feature that updates the wealth of 50 billionaires every 15 minutes.

Two-thirds say they often feel overwhelmed with responsibilities, and 6 in 10 caregivers are experiencing significant ups and downs in their moods.

"[In the past decade] there have been some significant ups and downs in demand, as political rhetoric and threats have spurred demand above the underlying normal rate of demand," Fifer wrote.

This analysis produced the same list of significant up and down-regulated genes.

Genes within this category showed both significant up and down regulation.

Statistically significant up and down regulated genes were analyzed separately in each accession for each time point.

Additionally, the specific gene responses we have analyzed and discussed here represent only a handful of the thousands of significant up and down regulated gene sets.

Not everyone can stomach the roller coaster ride of entrepreneurship which carries significant emotional ups and downs as the business struggles to gain profitability.