Under many of the scenarios, the south-west and northern England will see significant unmet demand".
The health department says these savings could be doubled, as there is still significant unmet need in Middlesbrough.
Such programs would respond to the significant unmet need that exists in Nauru in areas like child safeguarding and early childhood education.
Two in five (39%) parents who did not use holiday childcare said they would be very likely to use it if it were available – up from 37% in 2010, suggesting significant unmet demand, said 4Children.
There is a significant unmet need for well-designed clinical trials in NMO.
As a consequence, regeneration of the immune system remains a significant unmet clinical need.
There is significant unmet need in the treatment of lupus nephritis (LN) patients.
"There's no competing therapy that's very effective, so it's a significant unmet need," Prabhu added.
There is significant unmet medical need for new therapies to supplement the currently approved drugs.
Accomplishing these goals is urgent given the significant unmet needs in the pharmacological treatment of schizophrenia.
Regenerative therapy for heart failure remains a significant unmet need sin the global medical community.
