Suggestions(1)
Exact(6)
There was no clinically significant toxicity associated with the vaccine.
To date, however, there has been no proven benefit and there is significant toxicity associated with this treatment.
However, there can be significant toxicity associated with these combinations and historically, median survival has been 6 9 months.
Histological analysis of main organs (Supplementary Figure S17a) and monitoring of mice weight (Supplementary Figure S17b) did not indicate any significant toxicity associated with these treatments.
In conclusion, we have shown in a population-based study that there is no clinically significant toxicity associated with either past or present treatment for this condition.
There was no clinically significant toxicity associated with the vaccination even in the two patients who were given compassionate permission to continue being immunised for a 2-year period.
Similar(54)
It is clear that the efficacy of chemotherapy is limited by the development of drug resistance and the occurrence of significant toxicities associated with such agents.
This observation underscores the significant toxicities associated with such an intense treatment and this could limit the assessment of the true efficacy of this treatment strategy.
Most of these studies have revealed that the anionic surfactants are less toxic than nonionic surfactants, indicating significant specific toxicity associated with nonionic surfactants.
Thrombocytopenia was the most significant clinical toxicity associated with weekly PR-104 in this phase I study.
Despite the potential for large postnatal PCB exposures via breast milk, there is limited evidence of significant developmental toxicity associated with the transmission of moderate PCB concentrations through breast milk.
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