The uncertainty has had a significant toll on the OAIC.
This all takes a significant toll on mothers' and children's wellbeing.
Of the married respondents, 27percentt said their work took a significant toll on their relationship with their spouses.
No matter what the device, phone conversations appear to take a significant toll on attention and visual processing skills.
Despite austerity taking a significant toll, the economy has shown positive signs of recovery and Coelho's coalition has nudged ahead in recent polls.
Of Pfizer's share price, he added, "The real problem is that this is an expensive stock; a slight disappointment can take a significant toll".
It is becoming increasingly clear that this drought will take a significant toll on some of the nation's principal food crops, especially corn, wheat, and soybeans.
Treatments for prostate cancer take a significant toll on male potency, leaving a surprisingly high percentage of men unable to have a normal sex life, new research shows.
Despite rising levels of affluence in China, higher prices for fuel, cooking oil and other staples take a significant toll on the wallets of everyday workers.
The rating agency Fitch warned that firms were going to delay investment and hiring decisions as a result of the Brexit vote, taking a significant toll on the UK economy.
Howard Archer, chief economist at IHS Global Insight, said: "The fundamentals for consumers seem certain to progressively weaken over the coming months, which will take a significant toll on confidence as well as ability to spend.
