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The phrase "significant to someone" is correct and usable in written English.
It can be used to express that something holds importance or meaning for a particular individual or group. Example: "The award was significant to her, as it recognized her years of hard work and dedication."
Exact(3)
It's especially significant to someone like Pierce, an all-star who seems destined to forever exist inside mildly depressing coincidences.
It is wonderful to read a novel where the ageing main characters are not beset by dementia or care, but have the same desire as many of us: to know that they are significant to someone.
Furthermore, the biggest benefit of possessing belief is that it supports something that is significant to someone even if nobody else agrees with it.
Similar(56)
He said penalties are imposed only when it can be shown that the transactions provided a significant private benefit to someone "able to exercise substantial influence" over a charity.
Or that he was willing to give a nuclear or biological or significant chemical weapon to someone else who would risk using it against the United States.
I felt like someone significant to my life and to my family's life had walked away from us.
Some evenings, such as this one, he wishes that he had someone significant to share his life with.
At this point someone significant to the operation has a crisis of confidence, and, you've guessed it, only one man can save them.
And Susan Brison claims that "if one has an inadequate range of significant options to choose from, one's autonomy is diminished and the extent to which significant options are available to someone depends on the kind of society she lives in" (Brison 2000, 285).
The six minute clip had been shown to someone significant in the network production of the show, and the response had been, "Get me the Ink Spots".
And if you get on the wrong side of someone who's significant to an early contest, you might be kissing your chances in that contest goodbye.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com