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The technique has won recognition as a significant technological breakthrough.
A lightweight, air-cooled engine, Dr. Pisano and Dr. van der Linden said, "was the most significant technological breakthrough that would ensure the eventual conquest of the Atlantic Ocean by air".
Cliff Kupchan, an Iran specialist at the Eurasia Group, a Washington-based risk consultancy, said in a note to clients on Thursday that the faster centrifuges, assuming they work well, "would mark a significant technological breakthrough" that could shorten the amount of time Iran would need to create fuel for nuclear arms should it choose that path.
While EMSA, ChIP, luciferase assays, and 3C are widely applied and are mainstays in molecular genetic analysis, the development of high-throughput screening methods that can sensitively and accurately screen functional candidate variants would represent a significant technological breakthrough in this area.
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But for all the enthusiasm about harvesting sunlight, some of the most ardent experts and investors say that moving this energy source from niche to mainstream — last year it provided less than 0.01percentt of the country's electricity supply — is unlikely without significant technological breakthroughs.
However, significant technological breakthroughs are necessary for making a hydrogen economy feasible.
"We've had to make significant technological breakthroughs to allow computers to recognise their location accurately, quickly and in varying weather conditions," explains Miller.
Over the past 5 years, significant technological breakthroughs in imaging hardware and image processing algorithms have also been introduced, enabling specific radiotracer imaging for improved characterization of targeted cellular and functional processes in clinical routine.
Computational toxicology takes advantage of three significant technological breakthroughs: high-information-content data streams (e.g., from microarray or in vitro high-throughput screening experiments), novel biostatistical methods, and the computational power to analyze these data (Judson et al. 2009; Nigsch et al. 2009).
Rarely do tennis racquets represent important technological breakthroughs, but in addition to being an ideal racquet for recreational players, the Head i.S18 marks a significant development in "self-powered electronics".
In a polemical new book, "The Writing on the Wall: How Asian Orthography Curbs Creativity" (University of Pennsylvania Press), Mr. Hannas blames the writing systems of China, Japan and Korea for what he says is East Asia's failure to make significant scientific and technological breakthroughs compared to Western nations.
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