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Among other pre-Revolutionary song composers, Aleksandr Grechaninov and Sergey Rachmaninoff provided polished masterpieces, but no significant technical advances; more forward-looking are the early songs of Stravinsky and Sergey Prokofiev.
The future of intrusion prevention is likely to be marked by significant technical advances, but currently it is still strongly supported by its technological predecessor.
The first methods for visualizing RNAs within cells were designed for simple imaging of specific transcripts in cells or tissues and since then significant technical advances have been made in this field.
Significant technical advances such as the development of methods for radioligand binding, solubilization and purification of the β2-adrenoceptor and other adrenoceptors led to the cloning of receptor genes and the discovery of their 7TM architecture and homology with rhodopsin.
We will have to make significant technical advances in the security of personal computing devices and in network security before we can be sure that internet votes can be cast in a manner that approaches the privacy and security afforded by polling place voting.
Over the last twenty years, significant technical advances turned photogrammetry into a relevant tool for the integrated analysis of biogeomorphic cross-scale interactions within vegetated fluvial corridors, which will largely contribute to the development and improvement of self-sustainable river restoration efforts.
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"This certainly is a significant technical advance that is going to fuel more interest," said Dr. Michel Sadelain of the Memorial Sloan-Kettering Cancer Center.
The system of cryptographic software behind Bitcoin represents a significant technical advance, and the currency has inspired many cyber-libertarians (see "What Bitcoin Is and Why It Matters").
"The paper itself represents a significant technical advance because, rather than using the classic Crispr technology previously reported, the current 'base editor' technology is an adaptation that chemically alters the DNA bases themselves.
The new testing system, developed as a way to meet the requirements of the Federal Clean Air Act, is a significant technical advance over the familiar neighborhood-garage tailpipe test, which measures hydrocarbons and carbon monoxide, two of the three major pollutants from auto exhaust.
Still, the most significant technical advance in the 1920s was the abandonment of wooden structures in favour of metal frames (still fabric-covered) to provide the strength needed to cope with increasingly powerful engines and to resist harsh climates around the world.
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