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This is consistent with a significant structural change in the heme porphyrin ring structure, such as cleavage of the ring, and the generation of an intermediate or complex without absorbance characteristics.
Note that the inability of arrestin to bind in the presence of the Gtα peptide is unlikely to be a result of any significant structural change in the receptor caused by the peptide, because structures of metarhodopsin II with and without the peptide are very similar, with a root-mean-square deviation (rmsd) of 0.27 Å for all-atom alignment.
The article also misstated the date of the most recent significant structural change to the Internet.
But underneath, there is something more encouraging; the quiet riptide of communities adapting to significant, structural change.
However, the range of options open to PartyGaming is wide, and we expect significant structural change over the next 12-24 months. 12-24 months
Next says it has weathered its most challenging 12 months in 25 years as Britain's retail sector underwent significant "structural change".
Similar(8)
He was intent on making significant structural changes, including the creation of an 18-by-20-foot 18-by-20-foot 18-by-20-foot 18-by-20-footes.
It is the Dutch who are most opposed to making significant structural changes.
Last month Birmingham council's chief executive, Mark Rogers, told staff that "significant structural changes" to the local authority's education department were on the cards.
Raman spectroscopy revealed significant structural changes for GC electrodes treated by electrochemical oxidation and abrasive polishing.
Neo-neo induces significant structural changes in RNA where neomycin binds.
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