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Patients with significant stomach, small intestine, liver, or kidney disease likely to affect drug absorption or metabolism were excluded from the study.
This is believed to be a key factor in the etiology of clinically significant stomach ulcers in animals on low fiber diets [ 6, 7].
If the medication causes vision changes, difficulty breathing, dizziness, significant stomach upset, or other worrisome symptoms, consult a health professional immediately and ask about changing medications or dosages.
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Computed tomography showed a significant distended stomach with features of a severe gastric volvulus.
However, at 60 min p.i., a significant difference in stomach uptake was found in tumor-bearing animals with and without l-lysine, 0.9 ± 0.1%IA/g versus 1.6 ± 0.5%IA/g, P = 0.0079.
No significant toxicity except stomach irritation and general CNS depressant signs were observed.
A significant excess in stomach cancer was observed in non-Hispanic white males (SIR = 2.53, 95% CI = 1.09 4.99).
The significant improvement in stomach cancer survival in England and Wales since 1990 continues the trend observed since the early 1970s.
For individual sites, the majority showed a positive exposure response relationship (15 from 18), although this was significant only for stomach cancer.
In all these cases, no significant toxicity, except stomach irritation and general CNS depressant signs (reduced alertness and locomotion and diminished response to touch and balance) was observed.
There was no significant association with stomach cancer and gastric symptoms (RR=1.2, 95% CI=0.6 2.4), coffee drinking (RR=1.0, 95% CI=0.9 1.1), alcohol consumption (RR=1.0, 95% CI=0.9 1.1), or occupation (RR=1.0, 95% CI=0.9 1.1) in this study population, so these factors were excluded from the final model.
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