Using the microRNA microarray, we also noted the significant repression of multiple stemness-repressing miRNAs, such as miR-96 and miR-183, in the sphere-forming cells (unpublished finding).
Treatment of PMC42 cells with BMP7 resulted in a significant repression of the hTERT gene promoter.
Furthermore, as compared with AtHSFA2 knockout alone, double knockout with AtHSFA2 and AtHSFA4a or AtHSFA7a showed more significant repression of HS-induced GUS activity (Fig. 2b e).
The gene expression data show significant repression of PPARγ during the early phase of the high-fat response.
However, the overall observation of significant repression of Cx43 expression with hypoxia is consistent between both cell lines.
Significant repression of the transcriptional profiles in Meta was noted, particularly HLA-G in MHC I and HLA-DRB1 in MHC II.
Indeed, we detected a significant repression in luciferase activity when miR-20b was co-transfected with this vector expressing the 3'UTR of PPARγ (Fig. 3Aii).
These experiments indicated that most of the selected miRNAs produced a direct effect with significant repression of luciferase activity as compared with the controls (Figure 2).
This significant repression of tnaA at 15 h should decrease indole synthesis and contribute to enhanced biofilm formation for the hha mutant.
On the contrary, cotransfection of β-cateninΔN with AmphiVent2-luc resulted in a modest but significant repression of the reporter gene.
We show that mutating one putative Cds1 site in Yox1p results in significant repression of MBF targets during a DNA replication checkpoint response.
