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Analysts said this week's EU donation marks a significant repositioning.
One analyst described the changes as "the most significant repositioning" of a bank he had ever seen.
In a significant repositioning of his party, Mr Clegg called for a "tolerant Britain" that is "zero-tolerant of abuse".
In the only significant repositioning of a work, the painting now occupies an alcove off a second-floor balcony, opposite a great mural of dancing and tumbling nudes that Barnes commissioned from Matisse in 1929.
Birkdale recently had a face-lift that included lengthening it by 155 yards to 7,173 yards, which is plenty for a par-70 course; the addition of 20 new bunkers, the subtraction of 14 and the redesign or repositioning of 27 more; removal of trees to enhance its classic links look; and the rebuilding and significant repositioning of some greens, including the 17th, which was pushed back 25 yards.
The torsional flexibility ("wiggling") of the inhibitors can generate numerous conformational variants and the compactness of the inhibitors permits significant repositioning and reorientation (translation and rotation) within the pocket ("jiggling").
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In addition, Finnegan pointed out, O'Neal, during his first five years as C.E.O., "provided strong and decisive leadership during a phase of significant restructuring, repositioning, and growth for the company.
In a hematopoietic mouse cell line, we found mostly modest but significant radial nuclear repositioning of transcribed retroviral vector integration sites to more internal regions.
Apart from the ordering of L4, the most striking difference in the apo- and inhibitor-bound forms of MALT1 is found within L5, which undergoes a significant structural rearrangement, repositioning an important glutamine residue.
He said the firm's net profit had been hit by "significant investment to reposition the business", especially in its store network and its online presence, among other efforts.
"I would say it's a highly significant change; they're repositioning themselves," said Lauren Miller, the owner of MDesign, a graphic design firm in New York.
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