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Pragmatically, we identify magmatic unrest when magma is in motion (e.g., significant reactivation of convection in a magma chamber, of dyke intrusion).
The seismic reflection pattern within this entire assemblage suggests significant reactivation of small-scale faults prior to the Early Miocene that may have caused substantial deformation within the strata (Fig. 7).
Gene ontologic analysis of these EWS-FLI1-modulated targets confirms significant reactivation of neuroectodermal and concomitant repression of mesodermal differentiation programs in EWS-FLI1 expressing cells (Table S3B).
Follow-up ANOVAs indicated a significant reactivation × interference interaction for neutral, F 1,95) = 6.03, p<.02, η2 = 0.06, but not for positive or negative events, both F 1,95)<1.36, both p>.25, both η2<0.02.
In female hESC in which XIST is repressed, XACT is expressed from and coats both Xs, and this correlates with significant reactivation of the inactive X chromosome.
None of the obidoxime doses tested induced a significant reactivation of AChE or BuChE in blood at any time point (not shown).
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Two patients (multiple sclerosis, n = 1; systemic sclerosis, n = 1) had significant reactivations of herpesvirus infections early after HSCT and then developed aggressive EBV-PTLD and died on days +53 and +64.
Of the other 54 patients, 2 of whom had partial courses of rabbit ATG because of a reaction to the intravenous infusion of equine ATG, only 1 patient had a significant clinical reactivation of a herpesvirus infection (herpes simplex virus 2) early after HSCT, and none developed EBV-PTLD.
Given the low rate of ALT elevation observed, we suspect the rate of clinically significant HBV reactivation was low.
In addition, significant CMV reactivation was unlikely to occur in our patient cohort as they were not immunosuppressed owing to early initiation of therapy during the acute phase of infection and owing to the early stage of HIV disease progression.
In other HBV-endemic regions such as Hong Kong and Korea, several prospective studies of breast cancer patients receiving anthracycline-based chemotherapy have reported clinically significant HBV reactivation rate to be around 20 25% in HBsAg-positive patients who did not receive prophylactic antiviral therapy (Yeo et al, 2003; Kim et al, 2007).
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