Sentence examples for significant rationale from inspiring English sources

That is quite a significant rationale in acquiring Argos".

As EGFR and VEGFR expressions were shown to be important for NSCLC cancer, there is significant rationale behind the treatment of these tumours with BMS-690514.

A significant rationale for identifying RCC-associated hypermethylated TSGs is their potential role as biomarkers to identify high-risk individuals and presymptomatic tumours by analysis of urine samples (Battagli et al, 2003; Hoque et al, 2004).

44, 45 The discovery in 1991 that mutations in the tumor suppressor adenomatous polyposis coli (APC) 46, 47 were associated with >80% of sporadic colorectal cancers via aberrant activation of Wnt signaling provided significant rationale to therapeutically target this pathway.

Significant rationales for these collaborations include the high expectations placed on rapid and front-edge technology development and business exploitation.

Significant rationales for these innovation collaborations include the high expectations placed on rapid and front-edge technology development, better access to resources, and business exploitation (Goerzen 2007; Laperche and Liu 2013).

There is a significant scientific rationale to support the hypothesis that there might be a benefit to the use of carmustine wafers in the setting of adjuvant temozolomide and radiotherapy for glioblastoma.

Although this might be interpreted as a significant result, the rationale for choosing a one-tailed test might be debated.

However, closure decisions reflected significant variation in rationales, decision triggers, and authority for closure.

The 5-to-4 decision, legal experts said, was significant for rejecting the rationale behind the law, known as the "millionaire's amendment," and for confirming the court's continuing skepticism about the constitutionality of campaign finance regulations.

Nor are they likely to hear the owner's rationale for significant increases in ticket prices, or the MSG Network blackout that left Time Warner customers without Knicks and Rangers games for 48 days.