Sentence examples for significant rage from inspiring English sources

Furthermore, HF/HS diet triggered significant RAGE overexpression in the AM.

Because respiratory epithelial cells exposed to DPM resulted in significant RAGE up-regulation, we sought to uncover possible downstream signaling events in cells with increased RAGE.

Despite significant RAGE-mediated reductions in the inflammatory status of epithelial cells, the complete inflammatory profile of cells exposed to DPM is likely maintained by a complex array of molecules functioning in different yet parallel pathways.

These effects were strongly diminished in the presence of an anti-RAGE antibody, suggesting a significant role of RAGE in HMGB1-initiated pathogenic events.

Immunoblotting of cortical homogenates with anti-RAGE antibody showed significant reduction of RAGE expression levels in cerebral cortex of nRKO mice compared with non-Tg mice (∼80% reduction versus non-Tg brain, P<0.01).

We observed a significant induction of RAGE transcript levels in fibroblasts cultured on MG-collagen; 400%±12% upregulation of RAGE (Figure 8A, p<0.002).

Five years ago today, Syrians massed for the first significant "day of rage" protests on 15 March 2011, and the country has suffered terribly ever since.

Our earlier studies demonstrated that induction of I/R in the intact murine heart resulted in significant upregulation of RAGE, particularly in cardiomyocytes.

As shown in Table  2, we noted significant differences in RAGE mRNA expression in association with gender, age, the levels of protein induced by vitamin K absence or antagonist (PIVKA-II), and postoperative recurrence.

RAGE plays a significant role in inflammation-linked disorders such as Alzheimer's disease and atherosclerosis [ 26, 27].

Yet a significant number of Americans rage against taxes, and the party that controls all three branches of the federal government has made tax cuts its supreme priority.