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In conclusion, FT has significant prognostic values at 4 years in patients infected by HBV, similar to that of liver biopsy.
We also observed significant prognostic values for performance status in the present analysis.
Thike et al. [ 33] showed that basal cytokeratins had significant prognostic values, whereas EGFR did not in their patient cohort.
In the present study, maximum PINP, PIIINP and ICTP levels did not have statistically significant prognostic values for liver and renal failure in the ROC analysis.
In contrast, five other metagenes including the IL-8, Histone, VEGF, B-Cell, and T-Cell metagenes showed significant prognostic values when considered as continuous variables in univariate analysis (Additional file 2, Supplementary Table S4).
In stage III rectal cancer, R values were significant prognostic values in OS and DFS by multivariate analysis of prognostic factors, such as N-staging (P = 0.02, P = 0.002, respectively).
Similar(49)
In a series of landmark publications, MESA demonstrated that measures of subclinical cardiovascular disease add significant prognostic value to the traditional Framingham risk variables.
In the multivariate analyses, only the PR was of significant prognostic value (for PR⩾20 fmol/mg P=0.036, for PR⩾100 P=0.01, Cox analysis).
MELD score did not have significant prognostic value on ICU stay and early ICU mortality.
However, whether KDM6A mutation status holds significant prognostic value in cancer is yet to be determined.
Down-regulation of E-cadherin and up-regulation of type IV collagenase (MMP-9 and MMP-2) at the periphery of the neoplasms (P = 0.0167, 0.0102, and 0.0349, respectively) had significant prognostic value.
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