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It represents a big departure from her most significant previous role, in 2006's "Dreamgirls".
Was I really ready?" Ms. Knowles's most significant previous role was in 2006's "Dreamgirls," for which she earned a Golden Globe nomination.
Charged with a series of reviews since joining the Lords in 1998, Burns's most significant previous brush with the industry was to chair a review of the BBC's charter in 2006.
Three-quarters of the current students had full-time jobs in sports at one point -- not simply significant previous work experience.
The winner is part-owned by the former champion jockey Willie Carson, whose most significant previous involvement at the meeting had been Dayjur's last-gasp defeat at Belmont Park in 1990, when the brilliant sprinter threw away certain victory by jumping a shadow near the line.
Austin's most significant previous project, with Ida Benedetto, his romantic and creative partner, was the Illicit Couples' Retreat; it began when they stumbled on Penn Hills, an abandoned resort in the Poconos, and decided to redo seven rooms to create an "intimate adventure" for seven couples for one night.
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Maternal histories were significant for previous IUGR, recurrent or late pregnancy loss, NND or SB.
But the timing was significant, given previous EU criticism of his media crackdowns.
More significant than previous experience, though, was the fact that the Heat were playing at home.
Winners of the public vote at Toronto are seen as significant, with previous honourees including Life is Beautiful, Shine and Crouching Tiger, Hidden Dragon.
Scientists say this is significant as previous therapies needed to be given before symptoms even appeared.
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