The impasse has significant practical consequences.
"To do so would raise significant practical and ethical issues," the statement added.
The appointment would also create significant practical difficulties for the F.E.C.
George's specific remedy had no significant practical result, and few economists of reputation supported it.
Significant practical disruptions occasioned by plague, fire and war in the 1660s were in some ways less significant than issues of trust.
With a course like nursing, however, which has significant practical elements, how well can a distance-learning course replicate the experience of a university or college setting?
"Significant practical challenges remain in order to ensure that any register of beneficial ownership is accurate and robust, but we support government efforts to begin this process".
An injectable badger vaccine is available, but there are significant practical difficulties with it such as the need to repeatedly trap and vaccinate badgers each year.
The independent feasibility study published in 2015 found that resettlement could be viable, but also highlighted significant practical challenges, including the difficulty of establishing modern public services, healthcare, education and economic opportunities, particularly job prospects.
President Bush told President Vladimir V. Putin by telephone today that the United States would begin regarding Russia as a market economy, a change in semantics that has significant practical consequences for Russian-American trade.
I am in the process of trying to remortgage our family home with HSBC, and have encountered what I consider to be significant practical issues with one of the lending requirements.
