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Context:Streptococcus pyogenes has recently re-emerged as a significant pathogen causing disease ranging from pharyngitis to lethal systemic infection.
Staphylococcus aureus has emerged as a significant pathogen causing severe invasive disease in otherwise healthy people.
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Staphylococcus aureus is a significant human pathogen causing wound and skin infections, endocarditis and bacteremia [ 1, 2].
Streptococcus pneumoniae, or pneumococcus, is a significant human pathogen causing both mucosal, such as otitis media and pneumonia, and systemic diseases, including septicemia and meningitis.
Decades of research have consistently found RSV to be the most important viral pathogen causing significant acute respiratory illness in infants and young children [ 2, 5, 10, 43].
Additionally, both mutation rate and siderophore production have implications for bacterial virulence [8], [10], [16], [24], [38] and our study species is an important opportunistic human pathogen, causing significant morbidity and mortality among burns victims, intubated intensive-care patients and people with cystic fibrosis [39].
Cryptococcus neoformans, a basidiomycetous fungus of universal occurrence, is a significant opportunistic human pathogen causing meningitis.
Porcine reproductive and respiratory syndrome virus (PRRSV) is an emerging pathogen causing significant economic losses in the swine industry worldwide.
Staphylococcus aureus is a major human pathogen causing significant morbidity and mortality due to both community- and hospital-acquired infections.
Dengue virus (DENV) is a serious mosquito-borne pathogen causing significant global disease burden, either as classic dengue fever (DF) or in its most severe manifestation dengue hemorrhagic fever (DHF).
Bovine herpesvirus type 1 (BHV-1), a member of the subfamily Alphaherpesvirinae, is a virulent pathogen causing significant economic losses to the livestock industry, worldwide [ 1].
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