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Hence, FOXM1 also bound to a significant number of unique sites, suggesting that FOXM1 might uniquely control the transcription of specific sets of genes in a manner independent from ERα or that ERα might operate along with FOXM1 present at different sites via looping together of different chromatin locations.
We found little evidence of TALEN off-target effects, but each clonal line nevertheless harbors a significant number of unique mutations.
Furthermore each fp retrieved a significant number of unique targets which are not found by any other fp, further highlighting the utility of each fp.
However, a significant number of unique peptides in the liver 51-kDa subunit, skeletal muscle 56-kDa, and the brain 50-kDa and 60-kDa polypeptides were observed and suggest the existence of isoenzyme forms.
Meanwhile, each subtype is still characterized by a significant number of unique genes.
A significant number of unique OR genes in the pig genome may suggest the presence of swine specific olfactory stimulation.
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On the other hand, we also observed a significant number of OTUs unique to each individual across all subjects (ranged 25 63% in NHP; 49 62% in human subjects, Table 3).
As shown in Figure 3B, with the exception of products of unknown function, a significant number of the unique CDSs were associated with extracellular structures, i.e., fimbriae and trimeric autotransporters.
Pathway analysis also has limitations: i) although the intersections of hits among the 3 software packages IPA, MetaCore, and Pathway Studio were greater than the intersections among siRNA screens (Fig. 1B), a significant number of hits were unique to each software package; ii) as indicated above, the pathway analysis hits showed little intersection with siRNA screening hits.
Nevertheless, we found a significant number of aberrant target measurements unique to particular platform.
A significant number of ePKs were classified as unique, as they showed no clear affinity to any known group or family within the 4-kinome dataset.
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