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They actually don't find a statistically significant number of pathways common to the Wang and van't Veer lists (this fact is not emphasized, but see Figure 1 of their paper).
In the category of commercial databases, GENEGO, BIOCARTA and Applied Biosystems have significant number of pathways, whereas KEGG, REACTOME, NCI-PID and WikiPathways contain higher number of pathways in the category of academic databases.
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As expected from the significant number of common pathways among the three datasets, these 64 pathways from our HBV-HCC dataset were also effective in discriminating patients of public microarray datasets according to risk (log rank p-value < 0.001).
But the major concern is that their biosynthetic potential is much greater than that observed by fermentation, since a significant number of biosynthetic pathways remain dormant or under-expressed in conventional culture conditions (Cichewicz 2010).
In the current study, we found that RBf2 also associates with a significant number of signaling pathway gene promoters.
For both the nourishment and caste datasets, we identified which KEGG pathways had at least one DET, and we then performed a Fisher exact test to determine whether there is a statistically significant number of shared KEGG pathways with DETs given the number of unique pathways with DETs per each dataset and all pathways without DETs.
The reaction is sufficiently complex that a significant number of possible mechanistic pathways can be envisaged using the classical "arrow pushing" approach.
A significant number of genes and pathways were confirmed in an independent validation set containing 5 N1 controls, 5 N2 short-term and 6 M long-term practitioners.
A significant number of important metabolic pathways and functions associated with the unigenes were identified.
This translation would provide us with a significant number of well-understood pathways which can be directly simulated.
TNF and Ras can activate a significant number of the above noted pathways (p38, ERK, and NF-κB in particular) in generating cells with CD44+/CD24- phenotype.
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