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This review focuses on trends in the macromolecular recognition of biologically significant molecules (e.g., drugs, amino acids, steroids, nucleotide bases, carbohydrates, etc).
Synthetic networks that can be designed to recognize and bind biologically significant molecules are of great importance and influence a number of emerging technologies.
The successful adaptation suggests that the strategy and materials may be applicable to detecting/monitoring other medically significant molecules via sensor development.
Simple, fast and direct analysis or monitoring of significant molecules in complex biological samples is important for many biological study, clinical diagnosis and forensic investigations.
To address these questions, the molecular and cellular architecture of neoplastic tissue must be evaluated to identify functionally significant molecules to target for anticancer therapy.
Fifty images in Set I are obtained by querying pharmaceutically significant molecules to Google Image Search http://images.google.com/ so that the images have different drawing styles, sizes, font and resolutions.
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A second socially significant molecule that feeds these experimental animals is folic acid.
In particular, JAK1 is the most significant molecule involved in drug response.
Genistein is a socially significant molecule, in part because soy is an economically and socially important foodstuff (Whatmore, 2002).
The structural descriptors that were less significant, including molecules without benzene ring (models 1 and 2, Table 2) were present in the tested molecules with the lowest biological activity.
Glycoproteins are biologically significant large molecules that participate in numerous cellular activities.
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