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Current guidelines recommend that PD patients who are resistant to medical therapies, have significant medication side effects and lengthening off periods, but are otherwise cognitively intact and medically fit for surgery be considered for DBS.
The chi-square test was used to identify statistically significant medication overuse differences for dichotomous or categorical variables.
Approximately 60% of the medication errors occur at care transitions [3]. Lee et al. [4] showed that clinically significant medication transfer errors (MTEs) occur in 6 out of 10 patients when being shifted from one hospital ward to another.
All participants were asked about their general health and were excluded if they were on any significant medication (other than that for their glaucoma).
No significant medication effects on performance or brain activation were observed.
No significant medication effect on social competence was found despite clinical improvement on both medications.
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There was one significant medication-related adverse event which was reported as a critical incident.
Our findings suggest though that postoperative AED management in this TLE cohort may reflect a compromise between needing to relieve patients from significant medication-related side effects and confidence about surgical success.
Mantel-Haenszel chi-square tests suggested that the trends observed with increasing self-reported severity were significant for medication use and all core comorbidities (Table 2).
Owing to his significant co-medication for severe NYHA III problems and hypertension, sunitinib was started at a dose of 25 mg per day.
The system led to a significant reduction in medication orders with one or more medication errors (behaviour change) but not in preventable adverse events (no outcome change).
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