The breakup of A.M.D. is a major shift in the processor landscape, leaving Intel as the only significant maker of PC chips to still design and build its own products.
We also explored potential clinical use for significant genetic makers.
Will the results night suggest that Hollywood's best and most artistically significant film-makers are unable to cut it commercially?
In an interview with Reuters, Chen said he had no plans to shut down the company's handset business, thought to be a significant loss maker.
In my view, however, the most significant film-maker so far this century is the 67-year-old Austrian writer-director Michael Haneke, who came late to the cinema and even later to international fame.
Lynn Seymour, talking to Zoe Anderson, Independent, 2004 "No other significant dance-maker of the 20th-century had such a wildly fluctuating place in the ballet pantheon – from absolute adulation to utter dismissal".
However, her deal with ABC's daytime division for "The View," which she co-owns with the network, and which is both a ratings hit and significant profit maker, will remain in place.
One-third of straight plays have turned a profit on Broadway in recent years, though most of those are not significant money-makers on the scale of hits like "A Steady Rain," which starred Hugh Jackman and Daniel Craig on Broadway in 2009.
Do we want to become a medium-sized country with no great influence or responsbility in the world, abandoning our international role, or do we want to be part of a much bigger entity with far-reaching international influence in which we would be a significant decision-maker?
LG said its sales and profit for the first half of 2018 are at all-time highs but — and you knew a but was coming… — its smartphone division remains a significant loss-maker.
