First, selecting only the maximally significant locus without consideration for adjacent significance in either the 5 or 3' direction may produce artificially small peak boundaries.
The 530 Kbp physical region includes the BAC clone OJ1174_H11 harboring the most significant locus, RM18639, for the variation in FGP of the F2 population (Table 4; ANOVA).
Based on the reference rice genome database, the corresponding location was determined at 19.72 Mbp region, on a BAC clone OJ1174_H11, which also includes RM18639 - the most significant locus for the variation in FGP of the F2 population (Figure 3B).
This was evident in the writings of the intelligentsia of the time who constituted a significant locus of the opposition.
The most significant locus was observed on 5q35.1, harboring the SLIT3 gene (P = 2×10−3).
The most significant locus included SLIT3, CCDC99, and DOCK2 on 5q35.1.
One of these suggestive loci, that on chromosome 4, precisely overlapped the significant locus for basal cortical DOC levels.
The significant locus on MMU10 is syntenic to a region on human chromosome (HSA) 12 (Figure 3A).
The second significant locus spanned a 300 kb section of MMU9 (-logP = 7.32, gFWER-adjusted p value = 0.041) and only contained the gene Tmem108.
The one remaining significant locus encodes the flowering time control protein FCA and has only a single fixed noncoding site that differentiates Germany from Canada.
The most significant locus included a 646 kb duplication of SLIT3, CCDC99, and DOCK2 on 5q35.1 shared by 5 MDD cases.
