The sentence "significant lack of information" is correct and usable in written English.
You can use it whenever you want to express that there is a large amount of missing information on a certain topic. For example, "Despite extensive research, there remains a significant lack of information on the long-term effects of the medication."
Most areas of California farm country have a significant lack of information about their groundwater use.
Inspections are usually applied for defect detection in requirement documents or code modules, and there is a significant lack of information how inspections should be applied to OO design documents.
There is no doubt that there is a significant lack of information about bioenergy as well as biofuels especially when communicated to the general public [10].
There is, however, a significant lack of information.
But there is a significant lack of information available about this phenomenon.
However, there is a significant lack of information about the role of human factors influencing Norovirus infections.
There is a significant lack of available information regarding dynamic modeling and risk assessment of TENORM occupational exposure in the oil and gas industry, and available studies show that workers in the field are at risk of being exposed to varying levels of radiation.
Despite the Western media's fascination with the Kalashnikov-toting young Kurdish women fighting the Islamic State, there remains a significant lack of basic demographic information about these women.
Programmes for treating and managing MS should be underpinned by robust data, but it has been recognised that there is a significant lack of reliable, evidence-based information to inform service delivery and to generate important health service research on MS in the UK [ 3].
One of the main obstacles development practitioners face is the significant lack of quantitative and qualitative information collected and recorded on the number, growth, and characteristics of women-owned enterprises in the Arab world.
Environ Health Perspect 123:1–5; http://dx.doi.org/10.1289/ehp.1408601 There is a significant lack of health and safety information on most chemicals in the marketplace.
