Significant laboratory data demonstrated microcytic anemia (hemoglobin of 6.4 mg/dL) and normal coagulation times.
No pattern of clinically significant laboratory abnormalities could be attributed to exposure to HBOC-201.
Impact: Identified significant laboratory tests, risk adjusted data, and used logistic regression to predict an adverse event.
Significant laboratory values were leukocytosis of 12.5k/μL with 85% neutrophils and a normal lactic acid of 1.9 mmol/L (normal venous 0.5 2.2 mmol/L).
Efficacy of the optimal dose, as determined by rates of sustained virologic response at post-treatment week 12, ranged from 92%-10092%-100%ment wellwell tolerated and significant laboratory abnormalities were rare.clinicaltrials.gov Identifiers: NCT02243280 and NCT02243293.
His early collaboration with Steve Woolgar, Laboratory Life, was the first significant laboratory field study—one that initiated a series of such studies and in many ways transformed the sociology of science yet his work remains controversial within sociology and is not commonly known by scholars outside that field.
Significant laboratory findings were as follows: white blood cell count, 24,960 cells/mL; hemoglobin, 11.9 g/dL; platelet count, 185,000 cells/mL; aspartate aminotransferase, 386.5 U/L; alanine aminotransferase, 155.0 U/L; urea nitrogen, 22.77 mg/dL; creatinine, 1.56 mg/dL; and C-reactive protein, 1.65 mg/dL.
There were no significant laboratory abnormalities.
The significant laboratory and personnel resources required also limited the study size.
No severe (grade 3) adverse events occurred, nor any clinically significant laboratory abnormalities attributable to vaccination.
If any symptom is considered the sensitivity becomes 95.3% but such a strategy would result in a very large number of the HIV-positive population requiring laboratory investigation, requiring significant laboratory expansion and strengthening.
