Sentence examples for significant issues such as from inspiring English sources

More significant issues — such as why the government-provided security was so inadequate, despite Bhutto's repeated pleas for improvements — have been subsumed, at least temporarily, by a climate of suspicion and political maneuver in advance of the elections.

Epoxy adhesives have significant issues, such as the release of toxic fumes throughout curing, loss of strength and stiffness when exposed to hot temperatures, and low permeability and weakness to UV radiation.

While providing quality programs in jails is in no way a substitute for addressing significant issues, such as the use of money bail, unduly long case processing times, and general over-incarceration, that experience instilled in me a belief that incarceration should prepare people to succeed when they get back home.

When factors like these are not acknowledged, there is a risk that other significant issues such as power and hierarchy are muted [ 53].

The more rapid decline in plasma HIV-1 RNA for an INI-based versus an efavirenz-based regimen [ 34] makes the INI class attractive for patients with high viral loads or with significant issues, such as neurocognitive impairment.

A lot of modern research on materials is in the broad field of human healthcare and safety, involving significant issues such as protection from chemical and biological hazards, the detection of toxic combustions, and the development of novel, low-cost, point-of-care diagnostics.

"There seem to be significant gaps between the Russian and U.S. sides on these important issues such as Syria, missile defense and arms control," she said.

ZEBs have emerged in response to stringent environmental standards, both regulatory and voluntary, introduced to address increasingly significant environmental issues such as climate change, natural resource conservation, pollution, ecology, and population.