Sentence examples for significant issues is from inspiring English sources

There are many reasons for this, but clearly one of the significant issues is cost: the money and time needed to set up a new business, including regulatory and compliance costs, labor, infrastructure, and more.

But one of the significant issues is that TiO2-NPs are most likely to adsorb other organic contaminants in water based on their exceptional physicochemical properties, such as small size, high surface-to-mass ratio, and greater reactivity.

Nikiforakis et al. identify that one of the most significant issues is not that the generated fingerprints are unique but that they can be used to link the device across multiple visits [21].

For example, the White House and what I call the Obama thinness of being, the lack of "there there", in Gertrude Stein's words, on significant issues is disturbingly real to me.

A recent review of the CCB by The Health Council of Canada [ 26] has noted that one of the CCB's most significant issues is its problematically low uptake.

In the 80th Congress (1947-1948), fewer than 30percentt of significant issues were left unlegislated.

Severn Trent said it was trying to buy WM Sellbergs, a Swedish company, from Waste Management but no agreement had been reached as "significant issues" were yet to be resolved.

Such a small scale of commitment means that significant issues are simply not being examined, in particular the impact of policing on drugs use.

The Central Bank is facing calls to launch a full-scale investigation into a controversial unit run by Ulster Bank after significant issues were uncovered by an internal audit.

No significant issues were found that would stop development of the EEG recorder.

One of the most significant issues being debated is how the revenues generated though this system should be spent.