Sentence examples for significant issue given from inspiring English sources

This is a significant issue given its widespread practice.

This lack of research is a significant issue given the magnitude of this problem in the older adult population.

The main disadvantage of CSP plants is large space requirements, which are not a significant issue given the nature of the Atacama desert.

False positive fall reports were unlikely to be a significant issue given the high specificity of recall.

A common problem encountered in the home is the inability to adequately manage medications, which is a significant issue given that they are used to treat symptoms experienced by the patient, such as pain.

The first example has to do with international trade in conventional arms, which is a significant issue given the UK is one of the world's largest arms exporters [ 37].

Identifying and testing such workplace interventions to reduce work-family stress and conflict is an important public health issue, given the significant effects of high work-family conflict on the health and well-being of workers and their families (e.g., [ 1, 33]).

Methodologically, home practice is a pivotal issue, given that it may have a significant impact on intervention effects (Zenner et al., 2014), but is difficult to record accurately.

And that's a big issue given that the DfES and government ministers regularly talk about this as the most significant education reform for decades".

Cognitive impairment is a significant issue; due consideration should be given to the ethical and legal issues of capacity and consent.

Patient selection remains an important issue but, given the prevalence of BC, a significant number of treatments could be carried out in this way.