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Falling participation figures have been a significant issue for golf.
ABC executives said the prime-time ratings are not a significant issue for late night ratings.
He voted for President Bush, partly because guns were a significant issue for him.
"They see their attacks as a potentially significant issue for the president's re-election," he said.
This is a significant issue for Yahoo, and it will likely be long term and durational.
"The shortage on the 5S was a significant issue for the quarter," Mr. Shammo told Reuters.
"I think that is a significant issue for people," he said.
It is also a significant issue for soldiers returning from combat.
A significant issue for any would-be buyer is the status of Metro's London Underground distribution contract.
"It is such a significant issue for Australia and for the ability of Australians to take advantage of in terms of jobs and the economy," she says.
"It's a significant issue for us for a lot of reasons — environmentally, economically," said Peter Cutler, a spokesman for Mayor Byron W. Brown of Buffalo.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com